Nanotecnologie sotto la torre: caffè scientifici al CNI IIT@NEST a Pisa

IIT si racconta

Il 13 e il 27 maggio, presso il Caffè Letterario Volta Pagina di Pisa si terranno due incontri per scoprire le nanotecnologie, le tecnologie che lavorano sulla scala del miliardesimo di metro, con i ricercatori del Center for Nanotechnology Innovation dell’Istituto Italiano di Tecnologia di Pisa (CNI - IIT@NEST). La formula sarà quella degli ormai consolidati Caffè Scientifici organizzati da IIT a Genova. Un ambiente informale in cui conoscere i ricercatori dell’Istituto Italiano di Tecnologia e comprendere l’importanza della ricerca scientifica per il nostro futuro. L’iniziativa si rivolge ad un pubblico non specialistico e i ricercatori comunicheranno in un linguaggio accessibile a tutti la loro passione per la scienza.


Richard Shilton is winnner of Premio NEST 2015

Richard Shilton winner of NEST prize 2015

Prize is awarded to all young researchers under 35 years old, who carry out the activities at NEST, who have distinguished themselves for the publication in the nanotechnologies and nanoscience during the previous year with sponsorship from the company RIVOIRA.

This year stood out our young researcher, Richard Shilton, with the publication of the article "Nanoliter-Droplet Acoustic Streaming Ultra High Frequency Surface Acoustic Waves", published in Advanced Materials.


A new technique to study the movement of molecules inside cells

Pnas figure Researchers at the Center for Nanotechnology Innovation (CNI) of the Istituto Italiano di Tecnologia, in collaboration with the NEST Laboratory of Scuola Normale Superiore of Pisa and the University of California at Irvine have recently published a work on ‘Nature Communications’, one of the most prestigious scientific journals in the world, which could in principle revolutionize cell biology.
The study describes a new microscopy technique capable of investigating the movement of molecules, such as proteins, nucleic acids, and even ions, within the cell at unprecedented spatial and temporal resolution. The new technique has allowed identifying hitherto elusive intracellular water-filled nano-cavities used by molecules to efficiently move across the cellular environment and reach their destination.


Il Center for Nanotechnology Innovation all'IF2014

IF2014 La Scuola Normale Superiore e il Center for Nanotechnology Innovation dell'IIT parteciperanno all’Internet Festival 2014 con un collegamento dalla camera bianca del centro NEST in streaming verso l’auditorium del CNR. Tema della partecipazione (ore 17:30 del 10 Ottobre 2014) “Le materie prime del futuro: visita ai laboratori del NEST”, con il seguente abstract: Dai nanofili di semiconduttori ai dispositivi ibridi superconduttori-metallo normale, dal grafene alle nanoparticelle: il nanomondo si svela attraverso la microscopia elettronica a scansione (SEM). In diretta streaming dalla clean room del NEST per parlare di nanoscienza e nanostrutture e per “vedere e manipolare il nanomondo ed i nanomateriali” con l’aiuto degli elettroni . 

In collegamento dall'Auditorium del CNR : Camilla Coletti 



Aptamers: challenging targets

AptmarsThe discovery and realization of new molecular systems able to recognize with high precision a biological target have been recently described on the international journal Molecular Therapy Nucleic Acids . Authors are a research team composed by scientists of NEST, Scuola Normale Superiore and Istituto Nanoscienze-CNR, and of the Center for Nanotechnology Innovation, Istituto Italiano di Tecnologia.

The published results demonstrate that a special class of nucleic acid molecules, aptamers, is promising candidate as molecular systems for diagnostic and therapeutic applications, particularly when their targets are cell-surface receptors. In particular, researchers at CNI generated an enhanced DNA aptamer that selectively binds to the transferrin receptor, a cell-surface protein that is over-expressed in many tumors and on the endothelium of the blood brain barrier. They started from two interconvertible conformers of a known DNA aptamer, identified the active one, and engineered it to obtain an enhanced, more stable version by punctual mutations employing a rational optimization strategy. The improved aptamer represents a valid and innovative tool for targeted drug delivery both in vitro and in vivo.

For more information: Molecular Therapy - Nucleic Acids



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