Valerio Voliani

Researcher
Head of Translatable NanoTheranostics Unit

Research Lines

Electron Crystallography

Center

CNI@NEST Pisa

Contacts

p.zza San Silvestro, 12
+39 050 509888
+39050509888

Social profiles

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About

Valerio Voliani is a researcher at Center for Nanotechnology Innovation @NEST, Istituto Italiano di Tecnologia. He has obtained his MSc in Chemistry and PhD in Molecular Biophysics from Scuola Normale Superiore (Pisa, Italy). His efforts are devoted to the translation of noble metal nanomaterials to the bed-side by addressing the issue of metal persistence, in order to promote innovative and non-invasive treatments for neoplasms. By employing the ultrasmall-in-nano design, he has developed the passion fruit-like nano-architectures: an all-in-one inorganic nanomaterial able to jointly combine most of the intriguing behaviors of metal nanoparticles with their excretion from organism. His work is supported by an individual grant from Associazione Italiana per la Ricerca sul Cancro (AIRC). He is also actively engaged in scientific disseminations to students and community.

Interests

nanomedicine theranostics noble metals catalysis

Projects

• Jan 2018 – Jan 2023: Individual AIRC Grant MFAG 2017, number: 19852. Project: “Biodegradable noble metal-based nano-architectures as theranostics agents over head/neck neoplasms”.

• Jan 2018 – Jun 2018: Lions Club. Project: “Lions of Science”.

• Jun 2017 – Aug 2017: NIMS internship for PhD students “Investigations on the biodegradation mechanism of passion fruit-like nano-architectures”.

• Apr 2017 – May 2018: Materials Research Society Foundation Grassroots Grant. Project: “Boost-up the new generation of materials scientists”.

IIT Publications

  • 2019
  • Cassano D.iit, Summa M.iit, Pocovi-Martinez S., Mapanao A.-K.iit, Catelani T.iit, Bertorelli R.iit, Voliani V.iit
    DOI

    Biodegradable Ultrasmall-in-Nano Gold Architectures: Mid-Period In Vivo Distribution and Excretion Assessment

    Particle and Particle Systems Characterization, vol. 36, (no. 2)
  • Cassano D., Mapanao A.K., Summa M., Vlamidis Y., Giannone G., Santi M., Guzzolino E., Pitto L., Poliseno L., Bertorelli R., Voliani V.iit
    DOI

    Biosafety and biokinetics of noble metals: the impact of their chemical nature

    ACS Applied Bio Materials
  • Cassano D.iit, Santi M.iit, D'Autilia F.iit, Mapanao A.K.iit, Luin S., Voliani V.iit
    DOI

    Photothermal effect by NIR-responsive excretable ultrasmall-in-nano architectures

    Materials Horizons, vol. 6, (no. 3), pp. 531-537
  • Cassano D., Voliani V.iit

    Ultrasmall-in-nano approach: towards the clinical translation of metal nanomaterials

    Ultrasmall-in-nano approach: towards the clinical translation of metal nanomaterials
  • 2018
  • Cassano D., Voliani V.iit
    DOI

    Behaviors and Persistence of Nanomaterials in Biomedical Applications

    Behaviors and Persistence of Nanomaterials in Biomedical Applications, Publisher: Wiley Scrivener
  • d'Amora M.iit, Cassano D.iit, Pocovi-Martinez S., Giordani S.iit, Voliani V.iit
    DOI

    Biodistribution and biocompatibility of passion fruit-like nano-architectures in zebrafish

    Nanotoxicology, vol. 12, (no. 8), pp. 914-922
  • Vlamidis Y.iit, Voliani V.iit
    DOI

    Bringing again noble metal nanoparticles to the forefront of cancer therapy

    Frontiers in Bioengineering and Biotechnology, vol. 6, (no. OCT)
  • Armanetti P., Pocovi-Martinez S., Flori A., Avigo C., Cassano D.iit, Menichetti L., Voliani V.iit
    DOI

    Dual photoacoustic/ultrasound multi-parametric imaging from passion fruit-like nano-architectures

    Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 14, (no. 6), pp. 1787-1795
  • Mapanao A.K.iit, Santi M.iit, Faraci P., Cappello V.iit, Cassano D.iit, Voliani V.iit
    DOI

    Endogenously Triggerable Ultrasmall-in-Nano Architectures: Targeting Assessment on 3D Pancreatic Carcinoma Spheroids

    ACS Omega, vol. 3, (no. 9), pp. 11796-11801
  • Pocoví-Martínez S., Cassano D.iit, Voliani V.iit
    DOI

    Naked nanoparticles comprised in silica nanocapsules: a versatile family of nanorattle catalysts

    ACS applied nano materials, vol. 1, (no. 4), pp. 1836
  • Begarani F.iit, Cassano D.iit, Margheritis E.iit, Marotta R.iit, Cardarelli F., Voliani V.iit
    DOI

    Silica-based nanoparticles for protein encapsulation and delivery

    Nanomaterials, vol. 8, (no. 11)
  • Cassano D.iit, Pocovi-Martinez S., Voliani V.iit
    DOI

    Ultrasmall-in-Nano Approach: Enabling the Translation of Metal Nanomaterials to Clinics

    Bioconjugate Chemistry, vol. 29, (no. 1), pp. 4-16, Publisher: American Chemical Society
  • 2017
  • Avigo C., Cassano D.iit, Kusmic C., Voliani V.iit, Menichetti L.
    DOI

    Enhanced photoacoustic signal of passion fruit-like nanoarchitectures in a biological environment

    Journal of Physical Chemistry C, vol. 121, (no. 12), pp. 6955-6961
  • D'Apice R., Voliani V.iit
    DOI

    Increasing the metal loading in passion fruit-like nano-architectures

    Advanced Materials Letters, vol. 8, (no. 12), pp. 1156-1160
  • Cassano D.iit, David J.iit, Luin S., Voliani V.iit
    DOI

    Passion fruit-like nanoarchitectures: A general synthesis route

    Scientific Reports, vol. 7
  • Ranalli A., Santi M., Capriotti L.iit, Voliani V.iit, Porciani D.iit, Beltram F., Signore G.iit
    DOI

    Peptide-Based Stealth Nanoparticles for Targeted and pH-Triggered Delivery

    Bioconjugate Chemistry, vol. 28, (no. 2), pp. 627-635
  • Santi M.iit, Maccari G.iit, Mereghetti P.iit, Voliani V.iit, Rocchiccioli S., Ucciferri N., Luin S., Signore G.iit
    DOI

    Rational Design of a Transferrin-Binding Peptide Sequence Tailored to Targeted Nanoparticle Internalization

    Bioconjugate Chemistry, vol. 28, (no. 2), pp. 471-480
  • 2016
  • Cassano D.iit, Rota Martir D.iit, Signore G.iit, Avigo C., Menichetti L., Piazza V.iit, Voliani V.iit
    DOI

    Biodegradable nano-architectures containing gold nanoparticles arrays

    MRS Advances, vol. 1, (no. 30), pp. 2173-2179
  • Cassano D.iit, Santi M.iit, Cappello V.iit, Signore G.iit, Voliani V.iit
    DOI

    Biodegradable passion fruit-like nano-architectures as carriers for cisplatin prodrug

    Particle & Particle Systems Characterization, vol. 33, (no. 11), pp. 818-824
  • Cassano D.iit, Santi M.iit, Cappello V.iit, Luin S., Signore G.iit, Voliani V.iit
    DOI

    Biodegradable Passion Fruit-Like Nano-Architectures as Carriers for Cisplatin Prodrug

    Particle and Particle Systems Characterization, vol. 33, (no. 11), pp. 818-824
  • Cassano D.iit, Santi M.iit, Cappello V.iit, Signore G.iit, Voliani V.iit
    DOI

    Passion fruit-like nano-architectures as biodegradable inorganic theranostics to prevent accumulation in excretory system organs

    American Advanced Materials Congress
  • Rossi A.iit, Buch H.iit, Di Rienzo C.iit, Miseikis V.iit, Convertino D.iit, Al-Temimy A.iit, Voliani V.iit, Gemmi M.iit, Piazza V.iit, Coletti C.iit
    DOI

    Scalable synthesis of WS2 on graphene and h-BN: An all-2D platform for light-matter transduction

    2D Materials, vol. 3, (no. 3)
  • 2015
  • Cassano D.iit, Rota Martir D.iit, Signore G.iit, Piazza V.iit, Voliani V.iit
    DOI

    Biodegradable hollow silica nanospheres containing gold nanoparticle arrays

    Chemical Communications, vol. 51, (no. 49), pp. 9939-9941
  • Voliani V.iit

    Coating strategies for gold and lanthanides nanostructures with protocols

    Comprehensive guide for nanocoatings technology, pp. 65-79, Publisher: NOVA
  • Bergamini L., Voliani V.iit, Cappello V.iit, Nifosi R., Corni S.
    DOI

    Non-linear optical response by functionalized gold nanospheres: identifying design principles to maximize the molecular photo-release

    Nanoscale, vol. 7, (no. 32), pp. 13345-13357
  • Santi M., Maccari G., Mereghetti P., Boccardi C., Voliani V.iit, Rocchiccioli S., Piazza V., Beltram F., Signore G.

    Rational Design of Transferrin-Binding Peptide Sequences Tailored to Targeted Nanoparticles Internalization

    NanoMed
  • 2014
  • Vittorio O., Voliani V.iit, Faraci P., Karmakar B., Iemma F., Hampel S., Kavallaris M., Cirillo G.
    DOI

    Magnetic catechin-dextran conjugate as targeted therapeutic for pancreatic tumour cells

    Journal of Drug Targeting, vol. 22, (no. 5), pp. 408-415
  • Gonzalez-Bejar M., Liras M., Frances-Soriano L., Voliani V., Herranz-Perez V., Duran-Moreno M., Garcia-Verdugo J.M., Alarcon E.I., Scaiano J.C., Perez-Prieto J.
    DOI

    NIR excitation of upconversion nanohybrids containing a surface grafted Bodipy induces oxygen-mediated cancer cell death

    Journal of Materials Chemistry B, vol. 2, (no. 28), pp. 4554-4563
  • Voliani V.iit, Ricci F., Nifosi R., Luin S., Beltram F.

    Synergistic photo-release of drugs by non-linear excitation

    2014 Materials Research Society Spring Meeting and Exhibit
  • Voliani V.iit, Signore G.iit, Vittorio O., Faraci P., Luin S., Perez-Prieto J., Beltram F.
    DOI

    Synergistic photo-release of drugs by non-linear excitation

    Materials Research Society Symposium - Proceedings, vol. 1688
  • Voliani V.iit, Gemmi M.iit, Frances-Soriano L., Gonzalez-Bejar M., Perez-Prieto J.
    DOI

    Texture and phase recognition analysis of β-NaYF4 nanocrystals

    Journal of Physical Chemistry C, vol. 118, (no. 21), pp. 11404-11408
  • Meucci S.iit, Travagliati M.iit, Vittorio O., Cirillo G., Masini L.iit, Voliani V.iit, Picci N., Beltram F.iit, Tredicucci A., Cecchini M.
    DOI

    Tubeless biochip for chemical stimulation of cells in closed-bioreactors: Anti-cancer activity of the catechin-dextran conjugate

    RSC Advances, vol. 4, (no. 66), pp. 35017-35026
  • 2013
  • Voliani V., Signore G.iit, Vittorio O., Faraci P., Luin S., Perez-Prieto J., Beltram F.
    DOI

    Cancer phototherapy in living cells by multiphoton release of doxorubicin from gold nanospheres

    Journal of Materials Chemistry B, vol. 1, (no. 34), pp. 4225-4230
  • Voliani V., Perez-Prieto J.

    Fluorescent probes based on upconverting lanthanide nanostructures

    Fluorophores: Characterization, Synthesis and Applications, pp. 1-28, Publisher: Nova Science Publishers, Inc.
  • Voliani V., Gonzalez-Bejar M., Herranz-Perez V., Duran-Moreno M., Signore G.iit, Garcia-Verdugo J.M., Perez-Prieto J.
    DOI

    Orthogonal functionalisation of upconverting NaYF4 nanocrystals

    Chemistry - A European Journal, vol. 19, (no. 40), pp. 13538-13546
  • Voliani V.

    Recent Advances in Drug Delivery Research

    Recent Advances in Drug Delivery Research, Publisher: NOVA Science Publisher
  • Voliani V.

    Update on Gold Nanoparticles: From Cathedral Windows to Nanomedicine

    Update on Gold Nanoparticles: From Cathedral Windows to Nanomedicine, Publisher: Smithers Rapra Publishing
  • 2012
  • Voliani V.iit, Ricci F., Nifosi R., Perez-Prieto J., Luin S., Beltram F.

    Click-multifunctional gold nanospheres: a synergistic tool for controlled release

    women 2012 "workshop on nanomedicine and nanobiosystems"
  • Voliani V.iit, Ricci F., Luin S., Beltram F.

    Gold nanospheres for controlled drug-release by non-linear excitation

    Gordon Research Conference - Noble Metal Nanoparticles
  • Voliani V.iit, Ricci F., Luin S., Beltram F.iit
    DOI

    Peptidic coating for gold nanospheres multifunctionalizable with photostable and photolabile moieties

    Journal of Materials Chemistry, vol. 22, (no. 29), pp. 14487-14493
  • Voliani V.iit, Signore G.iit, Nifosì R.iit, Ricci F., Luin S., Beltram F.iit
    DOI

    Smart delivery and controlled drug release with gold nanoparticles: new frontiers in nanomedicine

    Recent Patents on Nanomedicine, vol. 2, (no. 1), pp. 34-44
  • Voliani V.iit, Signore G.iit, Nifosi R.iit, Ricci F., Luin S., Beltram F.iit

    Smart Delivery and Controlled Drug Release with Gold Nanoparticles:New Frontiers in Nanomedicine

    Recent Patents on Nanomedicine, vol. 2, pp. 34-44
  • 2011
  • Abbandonato G.iit, Signore G.iit, Nifosi R., Voliani V.iit, Bizzarri R.iit, Beltram F.iit
    DOI

    Cis-trans photoisomerization properties of GFP chromophore analogs

    European Biophysics Journal, vol. 40, (no. 11), pp. 1205-1214
  • Voliani V.iit, Ricci F., Nifosi R., Luin S., Beltram F.

    Multifunctionalized gold nanoparticles for smart intracellular delivery by non-linear excitation

    HYEX 2011 "international workshop on hybrid excitations in nanomaterials"
  • Voliani V.iit, Ricci F., Signore G.iit, Nifosi R., Luin S., Beltram F.iit
    DOI

    Multiphoton molecular photorelease in click-chemistry-functionalized gold nanoparticles

    Small, vol. 7, (no. 23), pp. 3271-3275
  • 2010
  • Voliani V.iit, Ricci F., Luin S., Beltram F.

    Single-step bifunctional coating for selectively conjugable nanoparticles

    Gordon Research Conference - Noble Metal Nanoparticles
  • Voliani V.iit, Luin S., Ricci F.iit, Beltram F.iit
    DOI

    Single-step bifunctional coating for selectively conjugable nanoparticles

    Nanoscale, vol. 2, (no. 12), pp. 2783-2789
  • Voliani V.iit, Luin S., Beltram F.iit
    DOI

    Single step coating and bifunctionalization of gold nanoparticles

    54th Biophysical Meeting, vol. 98, (no. 3), pp. 757-758
  • 2009
  • Luin S.iit, Voliani V.iit, Lanza G., Bizzarri R.iit, Nifosi R.iit, Amat P.iit, Tozzini V.iit, Serresi M.iit, Beltram F.iit
    DOI

    Raman study of chromophore states in photochromic fluorescent proteins

    Journal of the American Chemical Society, vol. 131, (no. 1), pp. 96-103
  • 2008
  • Voliani V.iit, Bizzarri R.iit, Nifosi R.iit, Abbruzzetti S., Grandi E., Viappiani C., Beltram F.iit
    DOI

    Cis-trans photoisomerization of fluorescent-protein chromophores

    Journal of Physical Chemistry B, vol. 112, (no. 34), pp. 10714-10722
  • Voliani V.iit, Bizzarri R., Beltram F.

    Photophysics of cis-trans isomerization in synthetic GFP chromophores

    52th Biophysical Meeting