Translatable NanoTheranostics

Translatable NanoTheranostics

Our efforts are devoted to the translation of noble metal nanomaterials to the bed-side by addressing the issue of metal persistence, in order to promote innovative and non-invasive treatments for neoplasms and infectious diseases.
By employing the ultrasmall-in-nano design, we have developed the passion fruit-like nano-architectures (WO2016/139591): an all-in-one inorganic nanomaterial able to jointly combine most of the intriguing behaviors of noble metal nanoparticles with their excretion from organism. Our main interests are related to photothermal conversion, drug delivery, photoacoustic/ultrasound imaging. In agreement with the 3R concept, we also continuously develop new 3D cancer models to test nanomaterials.
Thanks to the support of Fondazione AIRC we are especially working on combined treatments for head/neck neoplasms.
We are also involved in the development of novel nanorattle catalysts for hydrogen storage and automotive exhaust gas treatment.

IIT Publications List

Lai S., Vlamidis Y., Mishra N., Cosseddu P., Miseikis V., Ricci P.C., Voliani V., Coletti C., Bonfiglio A.
A Flexible, Transparent Chemosensor Integrating an Inkjet-Printed Organic Field-Effect Transistor and a Non-Covalently Functionalized Graphene Electrode
Advanced Materials Technologies
Ermini M.L., Voliani V.
Antimicrobial Nano-Agents: The Copper Age
ACS Nano, vol. 15, (no. 4), pp. 6008-6029
Sarogni P., Mapanao A.K., Marchetti S., Kusmic C., Voliani V.
A Standard Protocol for the Production and Bioevaluation of Ethical in Vivo Models of HPV-Negative Head and Neck Squamous Cell Carcinoma
ACS Pharmacology and Translational Science, vol. 4, (no. 3), pp. 1227-1234
Mapanao A.K., Santi M., Voliani V.
Combined chemo-photothermal treatment of three-dimensional head and neck squamous cell carcinomas by gold nano-architectures
Journal of Colloid and Interface Science, vol. 582, pp. 1003-1011
Pernakov M., Ermini M.L., Sulaieva O., Cassano D., Santucci M., Husak Y., Korniienko V., Giannone G., Yusupova A., Liubchak I., Hristova M.T., Savchenko A., Holubnycha V., Voliani V., Pogorielov M.
Complementary effect of non-persistent silver nano-architectures and chlorhexidine on infected wound healing
Biomedicines, vol. 9, (no. 9)


  • Prof. Gang Zheng, Princess Margaret Cancer Centre and TECHNA Institute (Toronto, CA)
  • Prof. Hélder Santos, University of Helsinki (Helsinki, FI)
  • Prof. Maksym Pogorielov, Medical Institute - Sumy State University (Sumy, UA)
  • Prof. Fabiola Paiar, Radiation Oncology - Pisa University Hospital (Pisa, IT)
  • Prof. Emanuele Neri, Department of Translational Research - University of Pisa (Pisa, IT)
  • Prof. Elisa Giovannetti, Department of Medical Oncology - Amsterdam University Medical Center (Amsterdam, NL)
  • Prof. Luca Menichetti, IFC-CNR (Pisa, IT)
  • Prof. Fabio Marchetti, Department of Chemistry and Industrial Chemistry - University of Pisa (Pisa, IT)
  • Prof. Alex Tovstolytkin, Institute of Magnetism - National Academy of Sciences of Ukraine (Kyiv, UA)
  • Dr. Rosalia Bertorelli, In vivo Facility - Istituto Italiano di Tecnologia (Genoa, IT)
  • Dr. Laura Poliseno, Oncogenomics Unit - Core Research Laboratory - CNR (Pisa, IT)
  • Dr. Orazio Vittorio, Children's Cancer Institute (Sydney, AU)
  • Dr. Giuseppe Cirillo, Università della Calabria (Cosenza, IT)

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